diff --git a/addons/web_editor/static/src/js/editor/odoo-editor/src/OdooEditor.js b/addons/web_editor/static/src/js/editor/odoo-editor/src/OdooEditor.js
index 309e9700477..d3d9e1bbf36 100644
--- a/addons/web_editor/static/src/js/editor/odoo-editor/src/OdooEditor.js
+++ b/addons/web_editor/static/src/js/editor/odoo-editor/src/OdooEditor.js
@@ -2230,7 +2230,8 @@ export class OdooEditor extends EventTarget {
      */
     _handleSelectionInTable(ev=undefined) {
         const selection = this.document.getSelection();
-        const anchorNode = selection.anchorNode;
+        // Selection could be gone if the document comes from an iframe that has been removed.
+        const anchorNode = selection && selection.getRangeAt(0) && selection.anchorNode;
         if (anchorNode && (closestElement(anchorNode, '[data-oe-protected="true"]') || !ancestors(anchorNode).includes(this.editable))) {
             return false;
         }