diff --git a/addons/web/static/src/core/popover/popover.js b/addons/web/static/src/core/popover/popover.js
index faab2cde600..aa0d7722cd7 100644
--- a/addons/web/static/src/core/popover/popover.js
+++ b/addons/web/static/src/core/popover/popover.js
@@ -1,9 +1,8 @@
 /** @odoo-module **/
 
-import { usePosition } from "../position_hook";
-
 import { Component } from "@odoo/owl";
 import { useForwardRefToParent } from "../utils/hooks";
+import { usePosition } from "@web/core/position_hook";
 
 export class Popover extends Component {
     setup() {
@@ -89,7 +88,14 @@ Popover.props = {
         type: Function,
         optional: true,
     },
-    target: HTMLElement,
+    target: {
+        validate: (target) => {
+            // target may be inside an iframe, so get the Element constructor
+            // to test against from its owner document's default view
+            const Element = target?.ownerDocument?.defaultView.Element;
+            return Boolean(Element) && target instanceof Element;
+        },
+    },
     slots: {
         type: Object,
         optional: true,
diff --git a/addons/web/static/src/core/position_hook.js b/addons/web/static/src/core/position_hook.js
index ea0556800bc..a6033b85f4f 100644
--- a/addons/web/static/src/core/position_hook.js
+++ b/addons/web/static/src/core/position_hook.js
@@ -1,7 +1,7 @@
 /** @odoo-module */
 
 import { useThrottleForAnimation } from "./utils/timing";
-import { useEffect, useExternalListener, useRef } from "@odoo/owl";
+import { useEffect, useRef } from "@odoo/owl";
 import { localization } from "@web/core/l10n/localization";
 
 /**
@@ -72,6 +72,20 @@ const DEFAULTS = {
     position: "bottom",
 };
 
+/**
+ * @param {HTMLElement} el
+ * @returns {HTMLIFrameElement?}
+ */
+function getIFrame(el) {
+    const parentDocument = el.ownerDocument.defaultView.parent?.document;
+    if (!parentDocument || parentDocument === el.ownerDocument) {
+        return;
+    }
+    return [...parentDocument.getElementsByTagName("iframe")].find((iframe) =>
+        iframe.contentDocument.contains(el)
+    );
+}
+
 /**
  * Returns the best positioning solution staying in the container or falls back
  * to the requested position.
@@ -82,19 +96,23 @@ const DEFAULTS = {
  *
  * @param {HTMLElement} target
  * @param {HTMLElement} popper
+ * @param {HTMLIFrameElement?} [iframe]
  * @param {Options} options
  * @returns {PositioningSolution} the best positioning solution, relative to
  *                                the containing block of the popper.
  *                                => can be applied to popper.style.(top|left)
  */
-function getBestPosition(target, popper, { container, margin, position }) {
+function getBestPosition(target, popper, iframe, { container, margin, position }) {
     // Retrieve directions and variants
     const [directionKey, variantKey = "middle"] = position.split("-");
     const directions =
         variantKey === "fit" ? FIT_FLIP_ORDER[directionKey] : DIRECTION_FLIP_ORDER[directionKey];
     const variants = VARIANT_FLIP_ORDER[variantKey];
 
-    if (typeof container === "function") {
+    // Retrieve container
+    if (!container) {
+        container = target.ownerDocument.documentElement;
+    } else if (typeof container === "function") {
         container = container();
     }
 
@@ -102,27 +120,28 @@ function getBestPosition(target, popper, { container, margin, position }) {
     const popBox = popper.getBoundingClientRect();
     const targetBox = target.getBoundingClientRect();
     const contBox = container.getBoundingClientRect();
+    const iframeBox = iframe?.getBoundingClientRect() || { top: 0, left: 0 };
 
-    const containerIsHTMLNode = container === document.firstElementChild;
+    const containerIsHTMLNode = container === container.ownerDocument.firstElementChild;
 
     // Compute positioning data
     /** @type {DirectionsData} */
     const directionsData = {
-        t: targetBox.top - popBox.height - margin,
-        b: targetBox.bottom + margin,
-        r: targetBox.right + margin,
-        l: targetBox.left - popBox.width - margin,
+        t: iframeBox.top + targetBox.top - popBox.height - margin,
+        b: iframeBox.top + targetBox.bottom + margin,
+        r: iframeBox.left + targetBox.right + margin,
+        l: iframeBox.left + targetBox.left - popBox.width - margin,
     };
     /** @type {VariantsData} */
     const variantsData = {
-        vf: targetBox.left,
-        vs: targetBox.left,
-        vm: targetBox.left + targetBox.width / 2 + -popBox.width / 2,
-        ve: targetBox.right - popBox.width,
-        hf: targetBox.top,
-        hs: targetBox.top,
-        hm: targetBox.top + targetBox.height / 2 + -popBox.height / 2,
-        he: targetBox.bottom - popBox.height,
+        vf: iframeBox.left + targetBox.left,
+        vs: iframeBox.left + targetBox.left,
+        vm: iframeBox.left + targetBox.left + targetBox.width / 2 + -popBox.width / 2,
+        ve: iframeBox.left + targetBox.right - popBox.width,
+        hf: iframeBox.top + targetBox.top,
+        hs: iframeBox.top + targetBox.top,
+        hm: iframeBox.top + targetBox.top + targetBox.height / 2 + -popBox.height / 2,
+        he: iframeBox.top + targetBox.bottom - popBox.height,
     };
 
     function getPositioningData(d = directions[0], v = variants[0], containerRestricted = false) {
@@ -211,11 +230,10 @@ function getBestPosition(target, popper, { container, margin, position }) {
  *
  * @param {HTMLElement} target
  * @param {HTMLElement} popper
+ * @param {HTMLIFrameElement} [iframe]
  * @param {Options} options
  */
-export function reposition(target, popper, options) {
-    options = { ...DEFAULTS, container: document.documentElement, ...options };
-
+export function reposition(target, popper, iframe, options) {
     let [directionKey, variantKey = "middle"] = options.position.split("-");
     if (localization.direction === "rtl") {
         if (["bottom", "top"].includes(directionKey)) {
@@ -234,7 +252,7 @@ export function reposition(target, popper, options) {
     popper.style.left = "0px";
 
     // Get best positioning solution and apply it
-    const position = getBestPosition(target, popper, options);
+    const position = getBestPosition(target, popper, iframe, options);
     const { top, left, variant } = position;
     popper.style.top = `${top}px`;
     popper.style.left = `${left}px`;
@@ -265,15 +283,31 @@ export function reposition(target, popper, options) {
  */
 export function usePosition(target, options) {
     const popperRef = useRef(options.popper || DEFAULTS.popper);
-    const getTarget = target instanceof HTMLElement ? () => target : target;
-    const update = () => {
-        const targetEl = getTarget();
-        if (popperRef.el && targetEl) {
-            reposition(targetEl, popperRef.el, options);
-        }
-    };
-    useEffect(update);
-    const throttledUpdate = useThrottleForAnimation(update);
-    useExternalListener(document, "scroll", throttledUpdate, { capture: true });
-    useExternalListener(window, "resize", throttledUpdate);
+    const getTarget = typeof target === "function" ? target : () => target;
+    const throttledReposition = useThrottleForAnimation(reposition);
+    useEffect(
+        (targetEl, popperEl) => {
+            if (!targetEl || !popperEl) {
+                return;
+            }
+
+            // Prepare
+            const targetDocument = targetEl.ownerDocument;
+            const iframe = getIFrame(targetEl);
+            const currentOptions = { ...DEFAULTS, ...options };
+
+            // Reposition
+            reposition(targetEl, popperEl, iframe, currentOptions);
+
+            // Attach listeners to keep the positioning up to date
+            const listener = () => throttledReposition(targetEl, popperEl, iframe, currentOptions);
+            targetDocument.addEventListener("scroll", listener, { capture: true });
+            window.addEventListener("resize", listener);
+            return () => {
+                targetDocument.removeEventListener("scroll", listener, { capture: true });
+                window.removeEventListener("resize", listener);
+            };
+        },
+        () => [getTarget(), popperRef.el]
+    );
 }
diff --git a/addons/web/static/src/views/fields/properties/properties_field.js b/addons/web/static/src/views/fields/properties/properties_field.js
index 4a917c37825..e40c3693833 100644
--- a/addons/web/static/src/views/fields/properties/properties_field.js
+++ b/addons/web/static/src/views/fields/properties/properties_field.js
@@ -349,7 +349,7 @@ export class PropertiesField extends Component {
             `.o_property_field[property-name="${propertyName}"] .o_field_property_open_popover`
         );
 
-        reposition(targetElement, popover, { position: "top", margin: 10 });
+        reposition(targetElement, popover, null, { position: "top", margin: 10 });
 
         const arrow = popover.querySelector(".popover-arrow");
         if (arrow) {
diff --git a/addons/web/static/tests/core/popover/popover_tests.js b/addons/web/static/tests/core/popover/popover_tests.js
index 9dba9b82b77..35e730608fb 100644
--- a/addons/web/static/tests/core/popover/popover_tests.js
+++ b/addons/web/static/tests/core/popover/popover_tests.js
@@ -3,7 +3,7 @@
 import { Popover } from "@web/core/popover/popover";
 import { usePosition } from "@web/core/position_hook";
 import { registerCleanup } from "../../helpers/cleanup";
-import { getFixture, mount, nextTick, triggerEvent } from "../../helpers/utils";
+import { getFixture, makeDeferred, mount, nextTick, triggerEvent } from "../../helpers/utils";
 
 let fixture;
 let popoverTarget;
@@ -159,3 +159,56 @@ QUnit.test("reposition popover should properly change classNames", async (assert
     );
     assert.strictEqual(arrow.className, "popover-arrow top-auto");
 });
+
+QUnit.test("within iframe", async (assert) => {
+    const iframe = document.createElement("iframe");
+    iframe.style.height = "200px";
+    iframe.srcdoc = `<div id="target" style="height:400px;">Within iframe</div>`;
+    const def = makeDeferred();
+    iframe.onload = def.resolve;
+    fixture.appendChild(iframe);
+    await def;
+
+    let popoverEl;
+    const TestPopover = class extends Popover {
+        onPositioned(el, { direction }) {
+            popoverEl = el;
+            assert.step(direction);
+        }
+    };
+
+    popoverTarget = iframe.contentDocument.getElementById("target");
+    await mount(TestPopover, fixture, {
+        props: { target: popoverTarget },
+    });
+    assert.verifySteps(["bottom"]);
+
+    // The popover should be rendered outside the iframe
+    assert.containsOnce(fixture, ".o_popover");
+    assert.strictEqual(
+        iframe.contentDocument.documentElement.querySelectorAll(".o_popover").length,
+        0
+    );
+
+    // The popover should be rendered in the correct position
+    const { top: targetTop, left: targetLeft } = popoverTarget.getBoundingClientRect();
+    const { top: iframeTop, left: iframeLeft } = iframe.getBoundingClientRect();
+    let popoverBox = popoverEl.getBoundingClientRect();
+    let expectedTop = iframeTop + targetTop + popoverTarget.offsetHeight;
+    let expectedLeft =
+        iframeLeft + targetLeft + popoverTarget.offsetWidth / 2 - popoverBox.width / 2;
+    assert.strictEqual(popoverBox.top, expectedTop);
+    assert.strictEqual(popoverBox.left, expectedLeft);
+
+    // Scrolling inside the iframe should reposition the popover accordingly
+    const scrollOffset = 100;
+    const scrollable = popoverTarget.ownerDocument.documentElement;
+    scrollable.scrollTop = scrollOffset;
+    await nextTick();
+    assert.verifySteps(["bottom"]);
+    popoverBox = popoverEl.getBoundingClientRect();
+    expectedTop = iframeTop + targetTop + popoverTarget.offsetHeight - scrollOffset;
+    expectedLeft = iframeLeft + targetLeft + popoverTarget.offsetWidth / 2 - popoverBox.width / 2;
+    assert.strictEqual(popoverBox.top, expectedTop);
+    assert.strictEqual(popoverBox.left, expectedLeft);
+});
diff --git a/addons/web/static/tests/core/position_hook_tests.js b/addons/web/static/tests/core/position_hook_tests.js
index 0d5f6cecd1f..bf7353f7e07 100644
--- a/addons/web/static/tests/core/position_hook_tests.js
+++ b/addons/web/static/tests/core/position_hook_tests.js
@@ -165,7 +165,7 @@ QUnit.test("is positioned relative to its containing block", async (assert) => {
 
     const popBox1 = document.getElementById("popper").getBoundingClientRect();
     destroy(popper);
-    document.getElementById("reference").remove();
+    document.getElementById("target").remove();
 
     // make container the containing block instead of the viewport
     container.style.contain = "layout";
diff --git a/addons/web_tour/static/src/tour_pointer/tour_pointer.js b/addons/web_tour/static/src/tour_pointer/tour_pointer.js
index 940430653ec..f7a6731192f 100644
--- a/addons/web_tour/static/src/tour_pointer/tour_pointer.js
+++ b/addons/web_tour/static/src/tour_pointer/tour_pointer.js
@@ -94,7 +94,7 @@ export class TourPointer extends Component {
                             const wouldOverflow =
                                 window.innerWidth - x - width / 2 < dimensions?.width;
                             el.classList.toggle("o_expand_left", wouldOverflow);
-                            reposition(anchor, el, {
+                            reposition(anchor, el, null, {
                                 position: this.position,
                                 margin: 6,
                                 onPositioned: (popper, position) => {