diff --git a/addons/stock/models/stock_move_line.py b/addons/stock/models/stock_move_line.py
index ff5154ee22a..bb6d19d6d46 100644
--- a/addons/stock/models/stock_move_line.py
+++ b/addons/stock/models/stock_move_line.py
@@ -408,9 +408,10 @@ class StockMoveLine(models.Model):
             for ml in self:
                 if ml.product_id.type != 'product' or ml.state == 'done':
                     continue
-                if 'quantity' in vals:
-                    new_reserved_qty = ml.product_uom_id._compute_quantity(
-                        vals['quantity'], ml.product_id.uom_id, rounding_method='HALF-UP')
+                if 'quantity' in vals or 'product_uom_id' in vals:
+                    new_ml_uom = updates.get('product_uom_id', ml.product_uom_id)
+                    new_reserved_qty = new_ml_uom._compute_quantity(
+                        vals.get('quantity', ml.quantity), ml.product_id.uom_id, rounding_method='HALF-UP')
                     # Make sure `reserved_uom_qty` is not negative.
                     if float_compare(new_reserved_qty, 0, precision_rounding=ml.product_id.uom_id.rounding) < 0:
                         raise UserError(_('Reserving a negative quantity is not allowed.'))
@@ -428,7 +429,7 @@ class StockMoveLine(models.Model):
                         lot=updates.get('lot_id', ml.lot_id), package=updates.get('package_id', ml.package_id),
                         owner=updates.get('owner_id', ml.owner_id))
 
-                if 'quantity' in vals and vals['quantity'] != ml.quantity:
+                if ('quantity' in vals and vals['quantity'] != ml.quantity) or 'product_uom_id' in vals:
                     moves_to_recompute_state |= ml.move_id
 
         # When editing a done move line, the reserved availability of a potential chained move is impacted. Take care of running again `_action_assign` on the concerned moves.
diff --git a/addons/stock/tests/test_move.py b/addons/stock/tests/test_move.py
index bef76702e97..0017e336cdd 100644
--- a/addons/stock/tests/test_move.py
+++ b/addons/stock/tests/test_move.py
@@ -6312,3 +6312,32 @@ class StockMove(TransactionCase):
             line_form.lot_ids.add(sn01)
         picking = picking_form.save()
         self.assertEqual(picking.move_ids_without_package.lot_ids, sn01)
+
+    def test_change_move_line_uom(self):
+        """Check the reserved_quantity of the quant is correctly updated when changing the UOM in the move line"""
+        Quant = self.env['stock.quant']
+        Quant._update_available_quantity(self.product, self.stock_location, 100)
+        quant = Quant._gather(self.product, self.stock_location)
+        move = self.env['stock.move'].create({
+            'name': 'Test move',
+            'product_id': self.product.id,
+            'product_uom_qty': 1,
+            'product_uom': self.product.uom_id.id,
+            'location_id': self.stock_location.id,
+            'location_dest_id': self.customer_location.id,
+        })
+        move._action_confirm()
+        move._action_assign()
+        ml = move.move_line_ids
+
+        # The product's uom is in units, which means we currently have 1 reserved unit
+        self.assertEqual(quant.reserved_quantity, 1)
+
+        # Firstly, we test changing the quantity and the uom together: 2 dozens = 24 reserved units
+        ml.write({'quantity': 2, 'product_uom_id': self.uom_dozen.id})
+        self.assertEqual(quant.reserved_quantity, 24)
+        self.assertEqual(ml.quantity * self.uom_dozen.ratio, 24)
+        # Secondly, we test changing only the uom: 2 units -> expected 2 units
+        ml.write({'product_uom_id': self.uom_unit.id})
+        self.assertEqual(quant.reserved_quantity, 2)
+        self.assertEqual(ml.quantity * self.uom_unit.ratio, 2)