diff --git a/addons/mail/static/src/components/attachment/attachment_tests.js b/addons/mail/static/src/components/attachment/attachment_tests.js
index b698c042825..2eb43d96f82 100644
--- a/addons/mail/static/src/components/attachment/attachment_tests.js
+++ b/addons/mail/static/src/components/attachment/attachment_tests.js
@@ -595,6 +595,41 @@ QUnit.test('close attachment viewer', async function (assert) {
     );
 });
 
+QUnit.test('clicking on the delete attachment button multiple times should do the rpc only once', async function (assert) {
+    assert.expect(2);
+    await this.start({
+        async mockRPC(route, args) {
+            if (args.method === "unlink" && args.model === "ir.attachment") {
+                assert.step('attachment_unlink');
+                return;
+            }
+            return this._super(...arguments);
+        },
+    });
+    const attachment = this.env.models['mail.attachment'].create({
+        filename: "test.txt",
+        id: 750,
+        mimetype: 'text/plain',
+        name: "test.txt",
+    });
+    await this.createAttachmentComponent(attachment, {
+        detailsMode: 'hover',
+    });
+    await afterNextRender(() => {
+        document.querySelector('.o_Attachment_actionUnlink').click();
+    });
+
+    await afterNextRender(() => {
+        document.querySelector('.o_AttachmentDeleteConfirmDialog_confirmButton').click();
+        document.querySelector('.o_AttachmentDeleteConfirmDialog_confirmButton').click();
+        document.querySelector('.o_AttachmentDeleteConfirmDialog_confirmButton').click();
+    });
+    assert.verifySteps(
+        ['attachment_unlink'],
+        "The unlink method must be called once"
+    );
+});
+
 });
 });
 });
diff --git a/addons/mail/static/src/models/attachment/attachment.js b/addons/mail/static/src/models/attachment/attachment.js
index 03edf5abcab..dc4d59d52de 100644
--- a/addons/mail/static/src/models/attachment/attachment.js
+++ b/addons/mail/static/src/models/attachment/attachment.js
@@ -97,12 +97,20 @@ function factory(dependencies) {
          * Remove this attachment globally.
          */
         async remove() {
+            if (this.isUnlinkPending) {
+                return;
+            }
             if (!this.isTemporary) {
-                await this.async(() => this.env.services.rpc({
-                    model: 'ir.attachment',
-                    method: 'unlink',
-                    args: [this.id],
-                }, { shadow: true }));
+                this.update({ isUnlinkPending: true });
+                try {
+                    await this.async(() => this.env.services.rpc({
+                        model: 'ir.attachment',
+                        method: 'unlink',
+                        args: [this.id],
+                    }, { shadow: true }));
+                } finally {
+                    this.update({ isUnlinkPending: false });
+                }
             } else if (this.uploadingAbortController) {
                 this.uploadingAbortController.abort();
             }
@@ -335,6 +343,12 @@ function factory(dependencies) {
             compute: '_computeIsTextFile',
             dependencies: ['fileType'],
         }),
+        /**
+         * True if an unlink RPC is pending, used to prevent multiple unlink attempts.
+         */
+        isUnlinkPending: attr({
+            default: false,
+        }),
         isViewable: attr({
             compute: '_computeIsViewable',
             dependencies: [